Jon is a co-founder, president, and board director of Corner Therapeutics. Outside of Corner, he is the Marian R. Neutra, PhD professor of pediatrics at Harvard Medical School and the director of Basic Research and Shwachman Chair in Gastroenterology at Boston Children’s Hospital. His lab’s primary research interest is to understand the molecular basis of inflammation and long-term protective immunity.

He has made significant discoveries in this area, most notably in the inflammatory pathways stimulated by Toll-like Receptors, RIG-I like Receptors, cGAS-STING and inflammasomes. His integrative analyses of innate signaling pathways have led to a comprehensive map of the subcellular sites of innate immune signaling. This map serves as the foundation of our understanding of the earliest stages of host-microbe interactions. Jon is an elected Fellow of the American Academy of Microbiology, and his work has been recognized with awards from the American Association of Immunologists, the Burroughs Welcome Fund and the International Endotoxin and Innate Immunity Society.

He received his PhD in microbial pathogenesis from Yale University under Dr. Craig Roy, and he performed postdoctoral training with HHMI Investigator Dr. Ruslan Medzhitov in the Immunobiology Department at the Yale University School of Medicine.