Partnering for a New Era of Medicine

Top of Mind Summit: Life Sciences is an invite-only conference for leaders and partners at the frontiers of the health care delivery, insurance, biotech, venture, and life sciences communities.

 

The Summit aims to provide participants with insights from UPMC, one of the nation’s largest integrated health systems that is forging a unique approach to the development of next-generation therapies and patient-focused health care delivery.

The Summit also is an opportunity to create valuable relationships with diverse stakeholders who are driving innovation in life sciences forward.  

Join leaders from Pfizer, Takeda, Network Bio, ElevateBio, PharmaLogic, Broad Institute, Bayer, Novo Nordisk, and other leading organizations for this intimate conference at the Center for Connected Medicine at UPMC.  

Attendees are strongly encouraged to plan to be at the Summit for the full event.

Highlighted
Speakers

Rick Siger

Commonwealth of Pennsylvania

Christina Isacson

Lightstone Ventures

Sean Hofherr

Broad Institute

David Moore

Novo Nordisk

Jeffrey Solomon

TD Cowen

Mike Diem

Pfizer Ventures

Jonathan Peacock

UCB and Avantor

Sonja Hess

AstraZeneca

Oscar Marroquin

UPMC

Diane Holder

UPMC Health Plan

Tim Billiar

UPMC

Jeanne Cunicelli

UPMC

Summit Program

September 9, 2024

11:00 a.m.-4:00 p.m.

Women’s Health @ Top of Mind Summit 

Women’s Health @ Top of Mind Summit is an exclusive pre-event opportunity at the Center for Connected Medicine in advance of the full Summit. This pre-event is dedicated to gathering stakeholders to drive discussion and solutions toward closing the existing gaps in women’s health and strategize actionable ways to foster innovation and discovery.

Agenda Highlights:

This year’s Summit theme is “Partnering for a New Era of Medicine,” and the women’s health program will approach partnering through a deep-dive into three key areas:

  • Research and clinical development as it affects the health of women
  • Gender differences in access to health care
  • Investment to drive innovations in women’s care

6:00-8:00 p.m.

Opening Reception

To kick-off Top of Mind Summit: Life Sciences, attendees will gather for an opening reception at the National Aviary in Pittsburgh. Enjoy getting to know your fellow attendees over drinks and hors d’oeuvres while taking in a unique Pittsburgh landmark. Transportation will be provided to and from the reception. 

September 10, 2024

7:30 a.m.

Registration opens, U.S. Steel Tower lobby

7:30-8:00 a.m.

Light Breakfast

8:00-8:30 a.m.

Opening Keynote: Enabling Life Changing Medicine

Change is constant – this is true in life and most certainly in health care. UPMC has always embraced change, innovation, and risk-taking, qualities that have translated into a successful track record of advances in health care delivery and system growth. Hear how these traits are now embodied in UPMC Enterprises, which enables strategic innovation across UPMC with the potential to significantly benefit patient care. 

Jeanne Cunicelli, Executive Vice President, UPMC and President, UPMC Enterprises

Jeffrey Solomon, President, TD Cowen

8:30-9:15 a.m.

The Long View: Creative Partnering to Solve Big Problems

Finding creative solutions to big problems doesn’t happen overnight. Strategic vision combined with a healthy appetite for smart risk-taking and tenacity are required to overcome challenges in health care. In this session, hear from seasoned industry leaders who have been key advisors to UPMC Enterprises and its portfolio companies about what it takes to be successful and why they chose to work with UPMC.  

Jonathan Peacock, Chair of the Board, Bluesphere Bio, UCB, and Avantor

David Moore, Executive Vice President, Corporate Development, Novo Nordisk

Steven Altschuler,

Matthias Kleinz, Executive Vice President

9:15-10:00 a.m.

Getting Close & Personal I: Strategies for Efficient Trials and Enhanced Patient Engagement

A critical early touchpoint and area for partnership between industry and health systems is in the clinical trials arena. Although traditional trials have resulted in many approvals, the model is facing challenges due to long timelines and high cost. This panel will explore opportunities for innovative approaches and partnerships that enhance the efficiency of clinical trials, increase patient engagement, and improve data quality.

Anantha Shekhar, Senior Vice Chancellor for the Health Sciences and Dean of the School of Medicine, University of Pittsburgh

José-Alain Sahel, Chair and Distinguished Professor, Department of Ophthalmology, University of Pittsburgh School of Medicine

Simon Dagenais, Senior Director, Real World Evidence, Pfizer

Beth Brooks, Head, Patient Insights and Behavioral Sciences, Sanofi

Nicole Ansani, Senior Vice President, UPMC Enterprises

10:00-10:25 a.m.

Coffee and Networking Break

10:25-11:20 a.m.

Manufacturing Change: Pennsylvania’s Efforts to Drive Innovation and Build Biotech Hubs

In this session, leaders from government, health care, and industry explore how Pennsylvania’s diverse economic landscape and rich manufacturing heritage offers compelling opportunities for life sciences investment. With opening remarks from the Commonwealth’s leading economic development official, the discussion will explore how the Keystone State’s nationally recognized health care and research institutions can be harnessed to advance thriving biotech ecosystems.

Rick Siger, Secretary of Community and Economic Development, Commonwealth of Pennsylvania

Mike Diem, Vice President, Pfizer Ventures

Kaigham “Ken” Gabriel, CEO, Pitt BioForge

Megan Shaw, CEO, Pittsburgh Life Sciences Alliance

Alison Beam, Senior Vice President and Chief Government Affairs Officer, UPMC

11:20 a.m.-12:00 p.m.

Keynote Fireside: The Evolving Health Care Landscape

Escalating prices and the mounting pressure on health insurers, employers, states, and Medicare to cover the cost of novel therapeutics has intensified in recent years. Is there a sustainable reimbursement model that will cover the costs, monitor efficacy, and ultimately drive value to the system? A leader debates the merits of various strategies.

Diane Holder, Executive Vice President, UPMC and President, UPMC Insurance Services Division

Deneen Vojta, President, Arctos Foundation

Feby Abraham, Executive Vice President and Chief Strategy Officer, Memorial Hermann Health System

James Bauersmith, Vice President, UPMC Enterprises

12:00-1:00 p.m.

Lunch 

1:00-1:40 p.m.

Getting Close & Personal II: Improving Patient Care Through Novel Biomarker Discovery

Precision medicine is expanding beyond oncology and advanced, complex biomarkers are emerging as key tools to segment patients with multi-factorial diseases. This session will feature diverse expert perspectives on the evolution of biomarker discovery in drug development and clinical care. It also will explore how multi-modal biomarkers and spatial omics can further enhance our understanding of complex biological processes to enable more effective treatments. Areas that will be discussed include the critical need for data sharing through innovative partnerships and the patient’s stake in accelerating the pace of discovery.

Sean Hofherr, Chief of Clinical Strategy and Product Development, Broad Clinical Labs

Sonja Hess, Senior Director, Centre of Genomics Research, Discovery Sciences, R&D BioPharmaceuticals, AstraZeneca

Tarek Samad, Head of Global Research and Corporate Patent & Trademark, Lundbeck

Tim Billiar, Executive Vice President and Chief Scientific Officer, UPMC

1:40-2:20 p.m.

Mind the Gaps: Driving Women’s Health Equity Through R&D, Investment, and Delivery of Care

There is growing awareness that significant gender inequities exist in health care. From gaps in our understanding of disease biology and clinical presentation between genders, to gaps in investment in R&D or access to care, these inequities stand in the way of delivering effective care to all patients irrespective of sex or gender. This panel will summarize the insights from the dedicated pre-event session on Monday to propose a path forward. 

Amy Meister, President, UPMC Community and Ambulatory Services

Caroline Gaynor, Partner, Lightstone Ventures

Robert Edwards, Chair, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh

Ketki Karanam, Vice President, UPMC Enterprises

Sandra Milligan, President of Clinical and Commercial Operations, Aspira Women’s Health

Michael Young, President and CEO, Temple University Health System

2:20-2:40 p.m.

Coffee and Networking Break

2:40-3:20 p.m.

Hiding in Plain Sight: Can AI Generate Real-World Insights to Solve Big Problems?

Health systems hold tremendously valuable data in their electronic patient record that could be a treasure trove for generating insights about new uses for existing medicines and the discovery of entirely new drugs. This panel will address what’s possible now and what’s needed in the future to effectively leverage AI in proactively developing new hypotheses and uncover new treatments from real-world data.

Milind Kamkolkar, Venture Partner, RA Capital Management

Sunita Badola, Senior Director, Head of Oncology Data Strategy and Partnerships, Takeda

Oscar Marroquin, Executive Vice President, UPMC and President, UPMC Physician Services

Andrew Epstein, Special Counsel, Cooley

Rob Hartman, Senior Director, UPMC Enterprises

Eli Casdin, Chief Investment Officer and Founder, Casdin Capital

3:20-4:00 p.m.

Partnering for Change: Collaboration is Key to Develop Novel, Complex Tx Modalities

Gene therapy, cell therapy, and radiopharmaceuticals, to name a few, are emerging modalities that are transforming care. While there is immense promise of these advanced therapies, there are unique manufacturing, supply chain, and clinical testing challenges to take these therapies from bench to bedside and ensure patients have easy access to innovative medicines. This panel will dive into several use cases where UPMC is partnering with industry to enable new therapies.

Don Yealy, Chief Medical Officer, UPMC

Etienne Montagut, President, PharmaLogic

Mike Paglia, Chief Technology Officer, ElevateBio

Frances L. Johnson, Chief Innovation Officer, Perspective Therapeutics

Leah Byrne, Founder and Chief Scientific Officer, Avista Therapeutics

Keir Loiacono, CEO, BlueSphere Bio

4:00-4:30 p.m.

Audience Discussion & Closing Remarks

Key themes that emerged from the day’s talks and next steps for the audience will be discussed.

Jonathan Peacock, Chair of the Board, Bluesphere Bio, UCB, and Avantor

Matthias Kleinz, Executive Vice President, UPMC Enterprises

5:00 p.m.

Summit closes 

Women’s Health @ Top of Mind Summit

Additional details and full agenda to come

Monday, Sept. 9, 2024

11:00 a.m.-4:00 p.m.

Women’s Health @ Top of Mind Summit is an exclusive pre-event opportunity at the Center for Connected Medicine in advance of the full Summit. This pre-event is dedicated to gathering stakeholders to drive discussion and solutions toward closing the existing gaps in women’s health and strategize actionable ways to foster innovation and discovery.

Agenda Highlights:

This year’s Summit theme is “Partnering for a New Era of Medicine,” and the women’s health program will approach partnering through a deep-dive into three key areas:

  • Research and clinical development as it affects the health of women
  • Gender differences in access to health care
  • Investment to drive innovations in women’s care

Summit Details

Where is the Summit?

The Top of Mind Summit: Life Sciences is held in the Center for Connected Medicine, which is on the 60th floor of the U.S. Steel Tower in downtown Pittsburgh. Our address is 600 Grant St., Pittsburgh, Pa, 15219.

Who are the attendees?

Executives in the pharmaceutical, biotech and venture capital industries, academics and founders in the life sciences space, and health system leaders.

Where should I stay?

The CCM reserves room blocks at a hotel that is a short walk of the U.S. Steel Tower. Booking information will be provided to registered attendees.

What is the closest airport?

The Pittsburgh International Airport is 18 miles from the U.S. Steel Tower. The drive can take 30-45 minutes depending on time of day. Ride share and taxi services are available.

How should I dress?

The attire for the Summit is business casual.

What if I have questions?

Please email the CCM team at topofmind@connectedmed.com.